Дорно дахины уламжлалт анагаах ухаан, 2011, 1(1)
ANTIHYPERGLYCAEMIC ANDANTIHYPERLIPIDAEMIC EFFECTS OF LONAL IN ALLOXAN-INDUCED DIABETIC RATS
( Тойм өгүүлэл )
Абстракт
Diabetic animals were randomly divided into 3 groups and treated orally with different
doses (100 mg/kg body weight) Lonal extract once a day for 21 days. The body weight of each
animal was determined, to assess any possible weight gain or loss in experimental animals
compared with control groups. On the 21st day, those administered 100 mg/kg of Lonal showed
more promising results with regard to fasting blood glucose (FBG), water intake when compared
to those treated with other doses. Therefore, 100 mg/kg dose was used for further biochemical
studies. Total cholesterol (TC), triglycerides (TG), Alat, Asat, ALP, low density lipoproteins (LDL)
and high density lipoproteins (HDL) levels, on normal and diabetic rats treated with the dose of
100 mg/kg, were evaluated.
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